Thrombomodulin anticorps

N° du produit ABIN1105877

L’anticorps Souris Monoclonal anti-Thrombomodulin a été validé pour FACS. Il convient pour détecter Thrombomodulin dans des échantillons de Humain.

Aperçu rapide pour Thrombomodulin anticorps (ABIN1105877)

Antigène: Thrombomodulin (THBD)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thrombomodulin est non-conjugé

Application: Flow Cytometry (FACS)

Clone: B-A35

Détail du produit anti-Thrombomodulin anticorps

Specificité: Recognises the soluble antigen. Recognises Thrombomodulin (TM), a 105 kDa protein.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ion Exchange Chromatography

Stérilité: 0.22 μm filtered

Immunogène: TF1 cell line.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, Sterile-filtered through 0.22 μm, Carrier and preservative free

Agent conservateur: Without preservative

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Thrombomodulin

Antigène: Thrombomodulin (THBD)

Autre désignation: CD141 / THBD

Sujet: CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII, thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.Synonyms: Fetomodulin, THRM, Thrombomodulin

ID gène: 7056

NCBI Accession: NP_000352

UniProt: P07204